online medical treatment

美肌内服薬|トラネキサム酸・シナール・ハイチオール

For those who feel that skincare alone is not enough and want to approach beauty from within, oral beauty supplements have become a popular choice. While they are all called oral beauty supplements, each ingredient has its own area of expertise. This page will explain the effects of Cinal, Tranexamic Acid, Yubela, Hi-Chlol, and Vitadan, and detail how to combine them to address different skin concerns.

  • ✓Shinarl (Vitamin C + Pantothenic acid) is a fundamental ingredient that suppresses melanin production and can also be expected to provide antioxidant benefits.
  • ✓Tranexamic acid is known to be effective in suppressing inflammatory responses, especially for melasma.
  • ✓Yubera (Vitamin E) is good for promoting blood circulation, and Hythiol (L-Cysteine) excels at melanin discharge and metabolism promotion.
  • ✓You can combine treatments according to your concerns, such as tranexamic acid + Cinal for melasma, or Juvela + Cinal for dullness.
Available daily from 9:00 AM to 10:00 PM
Available daily from 9:00 AM to 10:00 PM
5-minute walk from the station
5-minute walk from the station
A clean clinic with a white-based interior
A clean clinic with a white-based interior
Online consultations: same-day shipping at the earliest
Online consultations: same-day shipping at the earliest
Cosmetics and supplements sold exclusively at medical institutions are also available for purchase.
Cosmetics and supplements sold exclusively at medical institutions are also available for purchase.

We prescribe oral medications for beautiful skin through online consultations.

Including Tranexamic acid, Cinal, Vitadan, and Hithiol. Consultations are available daily from 9:00 AM to 10:00 PM, with same-day shipping possible.

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What are oral medications for beautiful skin?

Oral medications for beautiful skin are self-pay medications that help regulate skin cell turnover, suppress melanin production, and prevent skin aging through antioxidant effects, by ingesting ingredients such as vitamins and amino acids. Unlike topical (external) medications, their characteristic is that they can approach the entire body from the inside.

They are suitable for areas that are difficult to reach with topical medications, and for wide-area care such as the entire face, neck, and back. However, the changes are gradual. Please consider this type of treatment to be one that does not produce immediate results, but rather one where the difference becomes noticeable with continued use.

Differences between ingredients

Ingredient Name Main Action Specialty
Cinal (Vitamin C + Pantothenic acid) Antioxidant effect, suppression of melanin production, support for collagen production Prevention of spots, freckles, and post-inflammatory hyperpigmentation
Tranexamic acid Suppresses inflammatory reaction (plasmin activity) involved in melanin production Melasma, recurring pigmentation
Yuvela (Vitamin E: Tocopherol Nicotinate) Promotes peripheral blood circulation, antioxidant effect Dullness, poor skin tone due to poor blood circulation
Hithiol (L-cysteine) Promotes melanin excretion and metabolism, supports liver detoxification Rough skin, acne, spots, freckles
Vitadan (containing Vitamins B2 and B6) Regulates skin and mucous membrane cell turnover Angular cheilitis, rough skin, acne inflammation

Cinal (Vitamin C + Pantothenic acid)

Vitamin C (ascorbic acid) is said to suppress melanin production and also reduce existing melanin. It can also be expected to have an antioxidant effect to prevent skin aging, and in combination with pantothenic acid, it supports the skin's barrier function. It is a fundamental ingredient among oral beauty medicines and is often prescribed in combination with other ingredients.

Tranexamic acid

Originally used as a hemostatic agent and anti-inflammatory drug, tranexamic acid is now known for its effectiveness against melasma (pigmentation that appears symmetrically on the cheekbones), and its prescription for beauty purposes is becoming widespread. When inflammation occurs due to stimuli such as UV radiation or friction, melanocytes (cells that produce melanin) are activated. Tranexamic acid is believed to prevent excessive melanin production by suppressing the action of plasmin, which is involved in this inflammatory response.

Yuvela (Vitamin E)

Vitamin E has strong antioxidant properties and can also be expected to promote peripheral blood circulation. It is suitable for those with dullness due to poor circulation or those with cold sensitivity. When combined with Vitamin C, there is a synergistic effect that enhances their respective antioxidant actions.

Hithiol (L-cysteine)

L-cysteine is a type of amino acid that is said to promote the excretion and metabolism (turnover) of melanin. It also supports the liver's detoxification function and is used for a wide range of skin problems such as rough skin, acne, spots, and freckles.

Vitadan (containing Vitamins B2 and B6)

Vitamins B2 (riboflavin) and B6 (pyridoxine) work to regulate the turnover of skin and mucous membranes. They are often used for those who suffer from angular cheilitis, rough skin, or acne inflammation.

Approach to combinations

Oral beauty medications are said to be more effective when multiple ingredients are combined according to the purpose, rather than used as a single agent.

Concern Combination
Concerned about melasma Tranexamic acid + Cinal
Concerned about dullness/poor circulation Yuvela + Cinal
Concerned about acne/rough skin Hithiol + Vitadan
Basic set for overall skin beautification Cinal + Yuvela + Tranexamic acid

Our doctors will suggest combinations tailored to your concerns.

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目安

Oral beauty medications work in conjunction with the skin's regeneration cycle. They do not produce immediate changes.

Period Guideline
〜1 month You may start to feel changes in surface problems such as rough skin, angular cheilitis, and acne inflammation.
2〜3 months This is a period when you are likely to notice changes in skin tone and dullness. This should be your guide for evaluating effectiveness.
3〜6 months This is the time when changes in spots and melasma begin to appear. Continued use and sun protection are prerequisites.

Do not conclude that it is "ineffective" after one month; please continue for at least three months. Stopping midway will make the previous efforts less effective. Individual results may vary.

UV protection and combination with external preparations

For the care of spots and dullness, UV protection is as important as internal medication. Melanin is produced by UV stimulation, so continuing internal medication without using sunscreen will significantly reduce its effectiveness.

  • Please use sunscreen daily, regardless of season or weather.
  • Also use hats, parasols, and sunglasses.
  • Melasma can worsen with friction, so do not rub vigorously when washing your face or cleansing.

Furthermore, combining it with topical medications (such as hydroquinone) can lead to even greater effects. In particular, for melasma, the combined use of oral tranexamic acid and topical hydroquinone (such as Miramin) is sometimes recommended. For more details, please refer to the page on Whitening (Hyperpigmentation Care).

Combining "internal medication, external medication, and sun protection" is the most direct route to results.

Side effects and precautions

Main side effects

  • Tranexamic acid: Rarely, a risk of thrombosis has been reported. Other side effects include nausea, loss of appetite, and heartburn.
  • Vitamins C and E: These ingredients have relatively few side effects, but gastric discomfort may rarely occur.
  • L-cysteine: Rarely, allergic reactions such as rashes.
  • Vitamin B2: Urine may turn yellow, but this is due to the color of the ingredient and is not a cause for concern.

Those who cannot use or need to be careful with tranexamic acid

  • Those with a history of thrombosis (cerebral infarction, myocardial infarction, thrombophlebitis, etc.)
  • Those scheduled for surgery or requiring prolonged rest
  • Those using hemostatic agents (such as thrombin)
  • Pregnant or breastfeeding individuals
  • Those taking low-dose birth control pills: Both low-dose birth control pills and tranexamic acid are associated with the risk of thrombosis, so a doctor will determine whether co-administration is possible. Please be sure to inform us if you are taking birth control pills.

Symptoms requiring immediate medical attention

If you experience any of the following symptoms, stop taking the medication and seek medical attention immediately:

  • Calf pain and swelling (especially in one leg)
  • Sudden shortness of breath, chest pain
  • New or severe headache, blurred vision, numbness in limbs

Information on self-pay treatment

  • Cost: Oral medications for beautiful skin are self-pay and not covered by health insurance, so the full amount is self-funded.
  • Approval Status: All are domestically approved pharmaceuticals, but depending on the formulation, their use for cosmetic purposes may constitute off-label use.
  • Procurement Route: We use domestically approved products sourced through domestic pharmaceutical wholesalers. They are not individually imported products.
  • Risks: In cases of off-label use, side effects may not be covered by the pharmaceutical adverse reaction relief system.
  • Effectiveness: The degree of effectiveness varies individually, and not everyone will achieve the same results.

Prescription process at our clinic

STEP Content
1. Order and pre-medical questionnaire Please enter your skin concerns, medications/supplements you are currently taking, and medical history.
2. Online Consultation A doctor will determine the feasibility of the prescription and the appropriate combination of ingredients.
3. Shipping Same-day shipping is available at the earliest. Products are delivered in discreet packaging.
4. Continuation We also support continuous purchases and regular subscriptions. The guideline for evaluating effectiveness is 3 months.

Please try to continue for at least 3 months.

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よくあるご質問

Q. How long does it take to see results?
A. Considering the skin's regeneration cycle, it takes at least 2 to 3 months to experience noticeable changes. While skin irritation and angular cheilitis may show changes relatively quickly (within a few weeks), for spots and melasma, please continue for 3 to 6 months as a guideline. It is important to continue observing the progress rather than judging after one month. Individual results may vary.
Q. Which ingredients should I choose?
A. It depends on your concerns. For melasma and recurring pigmentation, the basic combination is tranexamic acid and Cinal. For dullness and poor circulation, Yuvela and Cinal. For acne and rough skin, Hithiol and Vitadan. If you are unsure, please inform us of your symptoms in the questionnaire, and our doctor will make a suggestion.
Q. Is sunscreen necessary?
A. Yes, it is. For the care of spots, melasma, and pigmentation, preventing UV exposure is as important as the treatment itself. If you continue only with internal medication but are still exposed to UV rays, the effect will be significantly reduced. Please use sunscreen daily regardless of the season, and also utilize hats and parasols.
Q. I'm taking low-dose birth control pills. Can I take them together?
A. Caution is needed if it includes tranexamic acid. Both low-dose birth control pills and tranexamic acid are associated with the risk of thrombosis, so a doctor will determine whether co-administration is possible during your consultation. Please be sure to inform us if you are taking birth control pills. Other ingredients (such as Vitamins C, E, L-cysteine) are generally easier to combine.
Q. How is it different from over-the-counter vitamins and supplements?
A. Prescription oral medications dispensed at medical institutions differ in that the content of ingredients is clear, and doctors select them after checking the patient's constitution and concomitant medications. However, some over-the-counter drugs contain the same ingredients. If you are already taking supplements, please inform us in the medical questionnaire to avoid duplication of ingredients.
Q. How long should I continue taking it?
A. Continue until your skin condition stabilizes, then adjust as needed while monitoring progress. If you continue tranexamic acid for a long period, please have your progress regularly checked by a doctor. We recommend reviewing your treatment periodically rather than continuing for long periods based on self-judgment.
Q. Are there any side effects?
A. While vitamins C and E are relatively low in side effects, stomach discomfort may rarely occur. Allergic reactions such as rashes have been reported rarely with L-cysteine. Tranexamic acid has been rarely associated with a risk of thrombosis, and individuals with a history of thrombosis cannot use it.
Q. Is health insurance applicable?
A. Our oral medications for beautiful skin are self-pay (out-of-pocket) treatments, so health insurance is not applicable. The appearance of effects and side effects varies from person to person.

Related Pages

よくある質問

Frequently Asked Questions

Q Should I drink all of them together?
A

You don't need to take all of them at once. You can choose and take the medications you need according to your specific skin concerns and goals. It is also possible to combine multiple medications.

Q How long does it take to feel the effects?
A

While there are individual differences, you are more likely to feel the effects with continuous use, aligning with your skin's natural turnover cycle (approximately 1 to 3 months).

Q Can it be used with topical medications (such as hydroquinone)?
A

Yes. A combination of oral medication and topical treatment is sometimes recommended, especially for melasma.

Q Can anyone use tranexamic acid?
A

Individuals with a history of thrombosis cannot use this product. Please inform your doctor of your medical history during your consultation.

Q トラネキサム酸は誰でも使えますか?
A

血栓症(脳梗塞・心筋梗塞等)の既往がある方、手術予定のある方は使用できません。低用量ピルを服用中の方も、どちらも血栓のリスクに関わるため併用の可否は医師が判断します。診察時に既往歴・服用中のお薬をお伝えください。

Q 日焼け止めは必要ですか?
A

必要です。メラニンは紫外線の刺激で作られるため、日焼け止めを使わずに内服だけを続けても効果が大きく削がれます。季節を問わず毎日使用してください。

Q 保険は使えますか?
A

当院の美肌内服は自由診療(自費)のため、健康保険は適用されません。効果や副作用の現れ方には個人差があります。

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