Urticaria medication can be prescribed and shipped online.
Order OnlineWhat is Urticaria (Hives)?
Urticaria, commonly known as hives, is a condition characterized by the sudden appearance of red, raised welts (wheals) on the skin, accompanied by intense itching. These wheals typically disappear within a few tens of minutes to 24 hours without leaving a trace. It is a very common condition, with 1 in 5 to 6 Japanese people experiencing it at least once in their lifetime.
While one might be inclined to search for a cause, like "Did I eat something bad?", the reality is that for about 70-80% of chronic urticaria cases lasting longer than 6 weeks, the cause cannot be identified through examination, making it "idiopathic."
Important: "Symptom Control" is more important than finding the cause.
International clinical guidelines for chronic urticaria with an unknown cause recommend that the basic treatment involvescontrolling symptoms with continuous use of second-generation antihistamines, rather than persistently searching for the cause.
In other words, in most cases, the treatment for urticaria doesn't require "special tests" but rather "appropriate prescription medication taken consistently." This treatment approach is highly compatible with online medical consultations, more so than traditional clinic visits.
Online consultations are suitable for these types of urticaria:
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Urticariarecurs multiple times a week (appearing and disappearing repeatedly)
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Appears in the evening to night and disappears by morning
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Over-the-counter anti-allergy medicationscannot control the itching
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Medication prescribed by a hospital previously was effective, butI stopped visiting and ran out of medication.
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I am busy andcannot spare time for dermatology waiting rooms.
Prescription second-generation antihistamines offer more options than over-the-counter medications, and doctors can adjust them based on symptoms and propensity for drowsiness.
Why does urticaria appear or worsen at night?
"It's fine during the day, but it appears at night" is a very common complaint. There are three main reasons:
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Diurnal variation in chronic urticaria
At night, the parasympathetic nervous system becomes dominant, making skin blood vessels more prone to dilation and histamine release. If "appearing in the evening to night and disappearing by morning" occurs almost daily, it is a sign of chronic urticaria. -
Cholinergic urticaria (triggered by bathing, exercise, sweating)
This type involves numerous small wheals (1-3mm) appearing every time body temperature rises, such as during a bath or under bedding. It is common in people aged 10-30. -
Accumulation of fatigue and stress
Stress and lack of sleep are not direct causes of urticaria, but they significantly act as exacerbating factors. Many people who experience recurrent urticaria only during busy periods fall into this pattern.
For all types, the primary treatment is antihistamines. It is recommended to start medication early rather than enduring sleep deprivation due to nocturnal symptoms.
Causes and Classification of Urticaria
Urticaria is a condition where histamine is released from mast cells in the skin, causing blood vessels to dilate and leading to itching and swelling. It can be acute or chronic.
|
Classification |
Duration/Characteristics |
|---|---|
|
Acute Urticaria |
Within 6 weeks. Often triggered by infections, food, or medication. |
|
Chronic Urticaria |
Lasting 6 weeks or more. About 70-80% are of unknown cause (idiopathic). |
Furthermore, they are classified by cause as follows:
|
Type |
Examples of Triggers |
|---|---|
|
Idiopathic |
Unknown cause. Most common. |
|
Physical |
Pressure, cold, heat, sunlight, friction, etc. |
|
Cholinergic |
Sweating due to exercise, bathing, tension. |
|
Food/Drug-induced |
Specific foods or medications (e.g., antipyretic analgesics, antibiotics). |
|
Infection-related |
Appears after colds or viral infections. |
"Dietary restriction will cure it" is a misconception.
For chronic urticaria with an unidentified cause, self-imposed dietary restrictions are unlikely to bring improvement and often only lead to nutritional imbalances. Unless specific allergens are confirmed, the basic approach is drug treatment while maintaining a normal diet.
Urticaria Treatment | Antihistamines as First-Line Choice
The cornerstone of treatment recommended by international guidelines issecond-generation antihistamines with minimal drowsiness.
|
Drug (Generic name/Example brand name) |
Characteristics |
|---|---|
|
Bilastine (Bilona) |
Very low drowsiness. Once a day. |
|
Fexofenadine (Allegra) |
Low drowsiness. Twice a day. |
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Desloratadine (Desalex) |
Low drowsiness. Once a day. |
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Olopatadine (Allelock) |
Stronger effect. May cause some drowsiness. |
* Actual prescriptions will be determined by a doctor after consultation, based on symptoms and lifestyle (e.g., driving, tolerance for drowsiness).
"Continuity" is key in treatment.
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Even if symptoms disappear, stopping medication too soon can lead to recurrence, socontinuous use for a certain periodis recommended.
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The goal is to gradually reduce and then stop the medication once symptoms subside.
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Most cases of chronic urticaria stabilize with consistent and appropriate medication control.
Topical medications (such as steroid ointments) generally have limited efficacy for urticaria, which is fundamentally an internal histamine reaction. For those who are "managing with topical medications but not getting better," please consider switching to oral treatment.
Precautions in Daily Life
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Hot baths, saunas, and strenuous exercise can worsen symptoms (opt for lukewarm showers).
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Alcohol and spices can dilate blood vessels and intensify itching.
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Avoid tight clothing and underwear.
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Lack of sleep, overwork, and stress are exacerbating factors. Be sure not to run out of medication, especially during busy periods.
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Cool itchy areas instead of scratching.
For the following symptoms, seek immediate emergency or in-person care instead of online consultation:
While urticaria alone is rarely life-threatening, the following symptoms may indicateanaphylaxis or angioedema. These are not suitable for online consultation.
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Difficulty breathing, wheezing, hoarseness → Call 119 immediately
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Swelling of the lips, tongue, or throat
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Low blood pressure, altered consciousness
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Eyelids swelling completely shut and lasting for several days
Additionally, if accompanied by fever or joint pain, or if the wheals remain in the same spot for more than 24 hours and leave marks, there might be another condition, and an in-person examination is recommended. Mona Clinic also has an in-person clinic (cosmetic dermatology, internal medicine, dermatology) in Aoyama. If an online consultation determines that an in-person examination is necessary, we will guide you accordingly.
Mona Clinic's Online Urticaria Consultation Process
- Book an appointment and complete the medical questionnaire on your smartphone (available daily from 9:00 to 22:00, year-round)
- Online consultation with a doctor—reviewing symptom progression, timing of appearance, and preferences regarding drowsiness
- Prescription of antihistamines and same-day shipping (fastest)—receive at home or convenience store
- Continuous treatment can also be completed online.Preventing medication shortages is key to controlling chronic urticaria.
Reasons why Mona Clinic is chosen
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Clear pricing system, including consultation fees and shipping (private practice)
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Fastest same-day shipping—to address "tonight's itch"
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Available daily from 9:00 to 22:00, year-round
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No clinic visits or waiting times. Consultations can be done during work or childcare.
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In cases requiring in-person care, we provide appropriate guidance to our Aoyama clinic, sister Jujo clinic, or partner medical institutions.
Urticaria is not a disease that "cannot be cured because the cause is unknown." The fastest way to recovery is to use the right medication, consistently, without interruption.





