ホーム > Juvelook (Skin Rejuvenation Injection) | Pores, Fine Wrinkles, and Firmness

Juvelook (Skin Rejuvenation Injection) | Pores, Fine Wrinkles, and Firmness

Juvelook (Skin Booster Injections) are performed at Mona Aoyama Clinic in Minami-Aoyama.

From ¥9,500 (tax included) / Open daily, 5-minute walk from Aoyama-Itchome Station.

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What is Juvelook?

Juvelook is a skin regeneration injection containing poly-D-L-lactic acid (PDLLA) and hyaluronic acid. The injected polylactic acid stimulates fibroblasts, promoting the production of collagen and elastin, thereby improving skin firmness, elasticity, and radiance from within.

Developed in Korea, it differs from immediate-acting hyaluronic acid fillers in its characteristic fundamental approach to nurturing the skin itself.

Expected Effects of Juvelook

  • Improved skin firmness and elasticity
  • Reduced appearance of pores
  • Improved fine lines and crepey wrinkles
  • Improved skin dullness and transparency
  • Uniform skin quality and texture

Effects vary from person to person.

Recommended for those who:

  • Are concerned about skin firmness and elasticity
  • Are concerned about open pores or rough skin texture
  • Are concerned about fine lines and crepey wrinkles
  • Want to fundamentally change their skin quality, which is difficult to improve with hyaluronic acid
  • Want to engage in anti-aging treatments

Mechanism of Action of Juvelook

Collagen Production by Polylactic Acid (PDLLA)

The main component of Juvelook, poly-D-L-lactic acid (PDLLA), stimulates fibroblasts in the skin after injection, promoting the natural production of collagen and elastin. The generated collagen forms a structure that supports skin firmness and elasticity, lifting the skin from within.

Synergistic Effect with Hyaluronic Acid

Juvelook also contains hyaluronic acid, which provides immediate moisturizing effects. Combined with the long-term collagen production effect of polylactic acid, both initial changes and sustained effects can be expected.

Progression to Visible Effects

Timing Condition
Immediately after treatment ~ 1 week Mild swelling and redness at the injection site begin to subside
1-2 months later Collagen production progresses, and improvements in firmness and elasticity begin to be felt
3-6 months later Maximum effect. Significant improvements in skin quality, pores, and fine lines
6 months ~ 1 year or more Effects persist. Regular additional treatments for further maintenance and improvement

Unlike immediate-acting hyaluronic acid, collagen production takes time. Many people begin to notice changes after 1-2 months, and the full effect is generally seen 3-6 months after the final treatment.

Difference from Rejuran

Injections aimed at skin regeneration include Rejuran in addition to Juvelook. Since their main ingredients and areas of expertise differ, the choice depends on your concerns.

Juvelook Rejuran
Main ingredient Polylactic acid (PDLLA) + hyaluronic acid Salmon-derived polynucleotide (PN)
How it works Stimulates fibroblasts to increase collagen Promotes skin regeneration and repair, reduces inflammation
Area of expertise Pores, skin firmness and elasticity, overall skin quality improvement Dryness, rough skin, fine lines, thin skin around the eyes
Onset of effects Appears gradually and lasts long Relatively quick to feel skin hydration

Which is more suitable depends on your skin condition, and sometimes a combination of both is used. For more details, please refer to the Rejuran page.

We will suggest a treatment plan tailored to your skin condition.

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About the Treatment

Main Treatment Areas

Entire Face

  • Cheeks / Jawline
  • Forehead / Temples
  • Around the mouth / Chin line

Partial Treatment

  • Areas with noticeable pores (around the nose, cheeks, etc.)
  • Areas with prominent fine lines

Injection into areas with thin skin will be decided after considering the properties of the product. For concerns around the eyes, we may suggest a different product.

Treatment Flow

STEP Content
1. Counseling and Examination We will confirm the areas of concern, your preferences, medical history, and medications.
2. Anesthetic Cream (Optional) For those concerned about pain, it will be applied for 15-20 minutes.
3. Injection A thin needle or cannula is used to inject small amounts into multiple points (15-30 minutes).
4. Aftercare After 5-10 minutes of rest, we will explain post-treatment precautions. Makeup is possible from the same day.

目安 (Estimated Number of Treatments and Frequency)

Purpose Recommended Sessions Interval
Initial Intensive Care 3-5 sessions Every 2-4 weeks
Maintenance/Additional Treatment 1-2 times a year As needed, depending on the effect

Multiple treatment sessions are necessary to achieve noticeable results. It is recommended to undergo 3-5 initial intensive sessions, followed by regular maintenance treatments for sustained effects.

Price

From ¥9,500 (tax included). Prices vary depending on the treatment area, volume, and number of sessions. For more details, please check the product page or contact us via our official LINE. As this is a private medical service, health insurance does not apply.

Side Effects and Downtime

Possible Symptoms After Treatment

Symptom Frequency Duration
Swelling and redness at the injection site Common 1-3 days
Bruising Occasional 1-2 weeks
Mild pain / Tenderness on pressure Common 2-5 days
Lumps/Nodules Occasional Several weeks to months (gradually absorbed)
Itching Rare 1-2 days

If lumpiness persists for a long time, or if redness and swelling continue for more than a week, or if pain worsens, please contact us immediately.

Who Cannot Undergo Treatment / Who Needs Caution

  • Pregnant or breastfeeding women (treatment not possible)
  • Those with infection, inflammation, or severe acne inflammation in the treatment area
  • Those with autoimmune diseases or keloid constitution
  • Those taking anticoagulants (blood thinners) (consultation required)
  • Those undergoing immune-suppressing treatment
  • Those whose diabetes is not well-controlled
  • Those who have had fillers injected in the same area (consultation required depending on the timing)
  • Those with allergies to the ingredients of the product

Precautions Before and After Treatment

Before Treatment

  • Please remove makeup from the treatment area before coming to the clinic.
  • Limit alcohol consumption the day before (increases risk of bruising).
  • Please reschedule if you are feeling unwell.

After Treatment

  • Do not press or rub the injection area strongly on the day of treatment.
  • Avoid strenuous exercise, sauna, and alcohol on the day of treatment.
  • Only shower (on the day of treatment to the next day).
  • Makeup is possible from the day of treatment.
  • Avoid peeling and laser treatments for 2 weeks.

Precautions Regarding Unapproved Medical Products, etc.

  • Unapproved Medical Product: The Juvelook used at our clinic is a medical product not approved in Japan.
  • Acquisition Route: It is imported by a doctor through individual import procedures (obtaining Yakkan Shomei from the regional health and welfare bureau).
  • Availability of Approved Medical Products in Japan: There are no medical products with the same ingredients or for the same purpose approved in Japan.
  • Information on Safety in Other Countries: This product was developed and is used in Korea. It has not received approval from the US FDA or similar bodies for the purpose of improving skin quality. Swelling, bruising, and lumps at the injection site have been reported.
  • Health Damage Relief System: Health damage caused by the use of unapproved medical products is not covered by the Pharmaceutical Side Effect Relief System.
  • Cost and Effects: As this is a private medical service, health insurance does not apply, and the full cost is borne by the patient. The extent of the effect varies from person to person.

Start with a consultation.

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Frequently Asked Questions

What is the difference from hyaluronic acid?
A. Hyaluronic acid immediately restores volume, but its effects last for about 6 months to 1 year. Juvelook, on the other hand, promotes collagen production, so it takes longer for the effects to appear, but it can lead to fundamental improvement in skin quality and more long-lasting results. Since they serve different purposes, they are sometimes used in combination.
How does it differ from Rejuran?
A. The main ingredients differ. Juvelook uses polylactic acid (PDLLA) to stimulate fibroblasts and increase collagen, making it effective for improving pores and firmness. Rejuran uses salmon-derived polynucleotide (PN) to promote skin regeneration and repair and soothe inflammation, and is also used for thin skin areas like around the eyes. They are used differently depending on the concern and can sometimes be combined.
Does it hurt?
A. There is a slight stinging sensation during the injection, but we use an ultra-fine needle and offer anesthetic cream. Many people say it was "less painful than expected."
How many sessions does it take to see results?
A. While individual results vary, many people start to notice changes after 1-2 months, and the effects stabilize after 3-5 sessions. Some individuals may experience changes after just one session, but the benefits accumulate with multiple treatments.
How long is the downtime?
A. There may be mild swelling and redness immediately after the treatment and on the following day, but for most people, this subsides within 1-3 days. Makeup can be applied from the same day, so it is a treatment with relatively little downtime. If bruising occurs, it will disappear within 1-2 weeks.
Can lumps form?
A. A temporary sensation of lumps may occur at the injection site. Most of these are naturally absorbed over several weeks to months. If you are concerned or if they persist for a long time, please contact us.
How long do the effects last?
A. The effects of improved firmness and elasticity due to collagen production can last for 6 months to over 1 year for some individuals. Regular maintenance treatments can help to prolong the effects even further.
Can it be combined with other treatments?
A. Yes, it can. Some people combine it with Botulinum Toxin injections to address wrinkles and sagging from multiple angles, while others combine it with fat-dissolving injections to improve both contour and skin quality simultaneously. However, please allow approximately 2 weeks after treatment before undergoing peeling or laser treatments. Please consult with your doctor during the examination regarding combinations.

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