What to do after sex without a condom - Actions you can take within 72 hours using DoxyPEP/PEP | Mona Aoyama Clinic

コンドームなしの性行為後にできること——ドキシPEP・PEPを使った72時間以内の対処法 | Mona青山クリニック

July 16, 2026

What to do after unprotected sex — How to deal with it within 72 hours using DoxyPEP and PEP

What to do within 72 hours after sexWe've organized a timeline of immediate actions you can take

"I had unprotected sex." "The condom broke." "I can't sleep from anxiety after it happened." — These situations can happen to anyone.

The important thing is to not panic, and take action by checking each measure available within 72 hours. After sex, the risk of HIV and STIs can be significantly reduced by using preventive medications at the appropriate time.

In this article, a doctor from Mona Aoyama Clinic explains what to do and in what order after unprotected sex, in an easy-to-understand timeline.

  • 24-hour reception, same-day prescription, same-day shipping available
  • Emergency prescriptions also available late at night (with late-night instant delivery option)
  • DoxyPEP + PEP simultaneous prescription also possible
Consult an online doctor now Check DoxyPEP costs

First, confirm — what you're concerned about changes the course of action

Concern Corresponding Medication/Action Time Limit
Concerned about HIV infection PEP (Post-Exposure Prophylaxis for HIV) Start within 72 hours of sex, continue for 28 days
Concerned about Chlamydia, Syphilis, Gonorrhea DoxyPEP Take 1 dose within 72 hours of sex
Concerned about pregnancy Emergency Contraception (Morning-after pill) Within 72 hours of sex (earlier is more effective)
Concerned about Hepatitis B (unvaccinated) Hepatitis B immune globulin + vaccine Ideally within 24 hours of sex

⏱️ All measures have a time limit of "within 72 hours (3 days)." Take action as soon as you realize. Our clinic offers 24-hour reception and same-day shipping.

Action Flow after Sex — Chronological Confirmation

  1. Calm down and assess the situationCheck how much time has passed since sex. If it's within 72 hours, preventive medication can be used.
  2. Determine if there's an HIV riskIf the partner's HIV status is unknown or positive, PEP is necessary. PEP is a different medication from DoxyPEP and needs to be taken daily for 28 days.
  3. Take DoxyPEP (STI prevention)If you're concerned about Chlamydia, Syphilis, or Gonorrhea, take a single 200mg dose of Doxycycline. As soon as possible, within 72 hours.
  4. Get PEP prescribed if necessary (HIV prevention)If there's an HIV risk, PEP can be prescribed in parallel with DoxyPEP. Our clinic offers both online.
  5. Get an STI test 2-4 weeks laterEven if you took DoxyPEP, there's a non-zero possibility of infection. Confirm with a test.
  6. Get an HIV test 4-6 weeks laterIf PEP was used, testing 4-6 weeks after completing the course is recommended.

Precautions when taking DoxyPEP (Emergency)

  • Take it as quickly as possible — most effective within 24 hours
  • It's ideal to take it after a meal, but in an emergency, it's okay to take it on an empty stomach (some nausea may occur but is acceptable)
  • Do not take with milk or antacids (reduces absorption)
  • Do not lie down for 30 minutes after taking it
  • Do not take it after 72 hours (it will not be effective)

If "you know nothing about your partner"

If your partner's HIV status or presence of STIs is unknown, it's safest to assume the worst-case scenario and act accordingly. If the sexual act carried an HIV risk (such as unprotected anal sex), consider both PEP and DoxyPEP.

⚠️ The riskiest action is to optimistically think "it will probably be fine" and let 72 hours pass. If you're hesitating, use that time to consult an online doctor.

Frequently Asked Questions

QI realized late at night. Can I get a prescription immediately?
A

Our clinic offers a late-night instant delivery option (10 PM - 9 AM). Please consult us even if you realize late at night. Also, by keeping DoxyPEP stocked at home in advance, you can respond immediately in such emergencies.

QCan I take PEP and DoxyPEP on the same day?
A

Yes, you can. DoxyPEP and PEP are different medications and can be used simultaneously. If you are concerned about both HIV and STIs, we recommend starting both on the same day.

QWhat should I do if symptoms appear after taking DoxyPEP?
A

If STI symptoms (urethral discharge, genital ulcers, rash, etc.) appear after taking DoxyPEP, it's possible the preventive effect was insufficient. Get an STI test immediately and start treatment.

QCan I keep DoxyPEP in stock in advance?
A

Yes, you can. Our clinic offers bulk purchase plans for 10, 20, and 30 doses. We recommend keeping it on hand in advance so you can respond immediately in an emergency.

Related Columns

What is DoxyPEP? A doctor explains the STI prevention medication to be taken within 72 hours after sex What's the difference between DoxyPEP, PrEP, and PEP? Comparing HIV and STI prevention medications Can DoxyPEP be prescribed via online consultation? Explaining the procedure and cost

Clinic Hours and Access (Online Consultation)

Clinic Name Mona Aoyama Clinic
Consultation Format Online consultation (nationwide) / In-person consultation (Tokyo, Aoyama)
Location D Building 3F, 1-10-3 Minami Aoyama, Minato-ku, Tokyo 107-0062
Nearest Station 5-minute walk from Tokyo Metro "Aoyama-itchome Station"
Online Consultation 24-hour reception, same-day shipping available (for payments by 4 PM)

For urgent consultations, contact Mona Aoyama Clinic

We offer 24-hour reception, same-day prescription, and late-night instant delivery.

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