Doxycycline Post-Exposure Prophylaxis (DoxyPEP) is a method of preventing sexually transmitted infections (STIs) such as syphilis, chlamydia, and gonorrhea by taking doxycycline after sexual activity.
When taken within 72 hours of sexual activity, it has been reported to reduce the risk of infection by:
・Syphilis: Approximately 87% ・Chlamydia: Approximately 88% ・Gonorrhea: Approximately 55%
DoxyPEP is not a drug that prevents HIV. If there is a risk of HIV infection, please consider using it in combination with PEP.
Recommended for:
・Those who have had sexual activity without a condom
・Those concerned about the risk of STIs
・Those who do not know their partner's infection status
・Those who want to prevent STIs in conjunction with PEP
The preventative effect decreases with time, so we recommend taking it as soon as possible after sexual activity (preferably within 24 hours, and no later than 72 hours).
Our clinic requires advance payment. Please proceed with the purchase for your desired plan first.
Indications
ドキシPEPは性行為後72時間以内に服用することで、
・梅毒 約87%
・クラミジア 約88%
・淋病 約55%
の感染リスクを低減する予防法です。
ドキシサイクリンが細菌の増殖を抑えることで、性感染症の発症リスクを低減します。
Directions and Dosage
Take 200mg (two 100mg tablets) as a single dose within 72 hours after sexual intercourse.
It is recommended to take it within 24 hours if possible.
Take with a glass of water and do not lie down for about 30 minutes after taking it.
If you are taking PEP, take Doxy-PEP approximately 2 hours after your PEP dose.
Regarding Fees
The displayed price includes the consultation fee and medication costs.
Side effects
Main side effects
・Nausea
・Stomach discomfort
・Abdominal pain
・Diarrhea
・Photosensitivity (skin becomes more prone to redness from sunlight)
If symptoms are severe, please consult a doctor.
Precautions for use
・Take within 72 hours after sex.
・Do not take within 2 hours of milk, calcium, iron supplements, or magnesium supplements.
・Do not lie down for 30 minutes after taking.
・We recommend using sunscreen while taking.
・DoxyPEP is not a drug that prevents HIV.
Contraindications - Who Should Not Use
・Those with allergies to tetracycline antibiotics.
・Pregnant or breastfeeding individuals.
・Individuals deemed unsuitable by a doctor.
About shipping
Depending on the size of your package and your preferences, you can choose between "Standard Delivery (Nekoposu)" or "Takkyubin Compact (+500 yen)."
Standard Delivery (Nekoposu)
Your package will be delivered to your mailbox.
You can receive it even if you are not home.
You cannot specify the delivery date or time.
Takkyubin Compact (+500 yen)
You will receive your package in person.
You can specify the delivery date and time.
Even after shipping, you can change the delivery date and time, or the pick-up location to a sales office or convenience store.
For more details on shipping methods, please refer to "About Shipping."
*Depending on your order details and the quantity of products, we may change to the most suitable shipping method. In such cases, no additional shipping fees will be incurred.
About Your Medication
・Name: Vibramycin Tablets 100mg
・Generic name: Doxycycline hydrochloride hydrate
・Manufacturer: Pfizer Japan Inc.
〈Clarification that the drug is not an approved pharmaceutical, etc.〉
Doxy-PEP is not approved in Japan for the purpose of preventing sexually transmitted infections (post-exposure prophylaxis) and is considered off-label use.
〈Clarification of acquisition route, etc.〉
The doxycycline used at our hospital is an domestically approved drug used off-label under the discretion of a physician.
〈Clarification of the existence of domestically approved pharmaceuticals, etc.〉
Doxycycline itself is a domestically approved drug, but its use for post-exposure prophylaxis (Doxy-PEP) of sexually transmitted infections is not approved.
〈Clarification of safety information, etc., in other countries〉
Doxy-PEP has been reported in overseas guidelines and clinical studies as a method to reduce the risk of syphilis, chlamydia, and gonorrhea infection. On the other hand, concerns about an increase in drug-resistant bacteria have also been raised, and it is important to use it appropriately under the supervision of a physician.
If you would like to consult with a counselor
Online Consultation: Although this is a guide after prepayment, you can change your order after placing it. If you wish to do so, please consult our official LINE account. In-person Consultation: Payment on the day of the consultation is also possible. Please make a reservation here for your desired plan first.
If a prescription cannot be issued based on a doctor's judgment, a full refund will be provided.
If you have any questions before making your payment, please feel free to contact us.
Our Hospital Information
住所:3F Minami Aoyama D Bldg., 1-10-3 Minami Aoyama, Minato-ku, Tokyo 107-0062
Take it within 72 hours after sexual intercourse. We recommend taking it within 24 hours if possible.
QCan I drink it every day?
A
The basic regimen is one dose after intercourse. Even if you have frequent intercourse, daily use is not recommended, and you should consult a doctor due to the risk of drug-resistant bacteria.
QWhat if I had sex multiple times on the same day?
A
If you have sex multiple times on the same day, one dose is sufficient. However, please wait at least 24 hours since your last dose.
QIs it okay to drink alcohol?
A
Although alcohol does not reduce the effectiveness of the medication, it may intensify side effects such as nausea. It is recommended to avoid alcohol consumption as much as possible.
QDoes taking Doxy-PEP prevent STIs 100%?
A
While DoxyPEP has been reported to reduce the risk of syphilis, chlamydia, and gonorrhea, it does not prevent 100% of infections. Also, since it does not prevent HIV or other STIs, we recommend using condoms and getting regular check-ups.
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How to Use Our Services
Online consultations require advance payment. Please select your desired plan and place an order.
For your first consultation, after placing your order, we will send you information about our web-based medical questionnaire and video consultation via LINE or email.
Shipment for both first and follow-up consultations will be made after a doctor's prescription is issued.
In-person consultations can also be paid for on the same day.
If you have any questions, please feel free to contact us via LINE.
① Place your order with your desired plan (for in-person consultations, please book online).
② Medical examination/counseling
③ Medication shipping (in-person consultations are treatments)