Does Placenta Injection Whiten Skin and Provide Anti-Aging Benefits? A Doctor Explains Its Effects, Frequency, Cost, and Impact on Blood Donation
Does placenta injection whiten skin? How many sessions does it take to see a difference? What are the differences between Laennec and Melsmon? The doctors at Mona Aoyama Clinic provide an honest explanation, including the fact that you will be permanently unable to donate blood.
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June 10, 2026
Does Placenta Injection Work for Whitening and Anti-Aging? Doctor Explains Effects, Frequency, Costs, and Impact on Blood Donation
and even the impact on blood donation.
"Does placenta injection really whiten skin?" "Which is better, Laennec or Melsmon?" "How many sessions before I see a change?" "Is it true I won't be able to donate blood?"—This one article will answer all your questions about placenta injections.
Placenta (placental extract) injection is a proven medication also used as an insured treatment for menopausal symptoms. For cosmetic purposes, it has been reported to have effects such as whitening, antioxidant, skin metabolism promotion, and fatigue recovery. Our clinic offers in-person treatment (in Aoyama, Tokyo).
- Placenta injections are available for in-person treatment (Aoyama, Tokyo)
- Combination plans with oral tranexamic acid can also be discussed
- Please start by consulting with us
1. What is Placenta? Differences between Laennec and Melsmon
Placenta is an extract from the placenta and contains many physiologically active substances such as amino acids, nucleic acids, growth factors, vitamins, and minerals. Two types of pharmaceuticals are approved in Japan.
| Item | Laennec | Melsmon |
|---|---|---|
| Origin | Pig placenta | Human placenta |
| Main Uses | Liver function improvement, beauty, fatigue recovery. Widely used in beauty clinics. | Insured for menopausal symptoms. Self-pay for cosmetic purposes. |
| Blood Donation | Permanently ineligible for blood donation | Permanently ineligible for blood donation |
2. Effects - An honest explanation of what improves
| Effect | Content | Strength of Evidence |
|---|---|---|
| Whitening / Pigmentation Improvement | Auxiliary suppression of melanin production by inhibiting tyrosinase activity | ○ Auxiliary |
| Antioxidant / Dullness Improvement | Removes active oxygen and reduces oxidative damage. Improves skin tone. | ○ |
| Firmness / Elasticity | Promotes collagen synthesis and activates fibroblasts | ○ |
| Fatigue Recovery / Energy Boost | Improves liver function and promotes systemic metabolism | ◎ Insured coverage実績あり |
| Alleviation of Menopausal Symptoms | Auxiliary action on hormone balance | ◎ Melsmon has insured coverage |
💡 The whitening and cosmetic effects of placenta injections are "auxiliary". For strong effects on dark spots and melasma, a combination with oral tranexamic acid and topical hydroquinone is most effective. We can guide you through combination plans with online prescriptions.
3. How many sessions are needed? Recommended Schedule
| Phase | Frequency | Approximate Period |
|---|---|---|
| Initial Phase (to achieve effects) | 1-2 times per week | 1-2 months |
| Maintenance Phase (to sustain effects) | 1-2 times per month | Ongoing |
There are individual differences in when effects are felt, but some people notice "brighter skin" or "less fatigue" after 3-5 sessions. For whitening and spot treatment, continued use for 2-3 months is recommended.
4. Impact on Blood Donation - Important Precautions
⚠️ Receiving placenta injections will permanently disqualify you from donating blood. According to Japanese Red Cross Society regulations, individuals who have received placenta injections, regardless of human or porcine origin, cannot donate blood. Please confirm this before applying for the procedure. This is an irreversible choice.
5. Combination with Tranexamic Acid and Juvelook
| Combination | Effects | Availability |
|---|---|---|
| Placenta Injection + Oral Tranexamic Acid | Synergistic effect of fundamental melasma suppression + antioxidant action | ✅ Placenta: In-person / Tranexamic Acid: Online prescription |
| Placenta Injection + Juvelook | Comprehensive anti-aging care with antioxidant & metabolism promotion + collagen production boost | ✅ Both are in-person treatments |
| Placenta Injection + Topical Hydroquinone | Antioxidant action from within while suppressing melanin production from without | ✅ Placenta: In-person / Hydroquinone: Online prescription |
6. Frequently Asked Questions
We use a fine needle, so the pain is minimal. There's only a slight stinging sensation at the injection site, and many people say, "It wasn't as painful as I expected."
We do not recommend placenta injections for those who wish to donate blood. Once you receive them, you will be permanently unable to donate blood. For whitening and antioxidant purposes, we can suggest alternatives that do not affect blood donation, such as oral tranexamic acid or oral vitamin C.
Yes, it can. By combining oral tranexamic acid (online prescription) to suppress melanin production from within with placenta injections to promote antioxidant and metabolic activity, a synergistic effect can be expected.
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| Clinic Name | Mona Aoyama Clinic |
| Consultation Format | Online Consultation (nationwide) / In-person Consultation (Aoyama, Tokyo) |
| Location | D Building 3F, 1-10-3 Minami Aoyama, Minato-ku, Tokyo 107-0062 |
| Nearest Station | 5-minute walk from "Aoyama-itchome Station" on the Tokyo Metro |
| Online Consultation | 24-hour reception / Same-day shipping available (for payments by 4 PM) |
Consult Mona Aoyama Clinic for Placenta Injections
We offer placenta injections for whitening and anti-aging purposes with in-person treatment (Aoyama, Tokyo).